Deficient Regulatory T Cell Activity and Low Frequency of IL-17-Producing T Cells Correlate with the Extent of Cardiomyopathy in Human Chagas' Disease

BACKGROUND: Myocardium damage during Chagas' disease results from the immunological imbalance between pro- and production of anti-inflammatory cytokines and has been explained based on the Th1–Th2 dichotomy and regulatory T cell activity. Recently, we demonstrated that IL-17 produced during exp...

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Detalles Bibliográficos
Autores principales: Guedes, Paulo Marcos Matta, Gutierrez, Fredy Roberto Salazar, Silva, Grace Kelly, Dellalibera-Joviliano, Renata, Rodrigues, Gerson Jhonatan, Bendhack, Lusiane Maria, Rassi, Anis, Schmidt, André, Maciel, Benedito Carlos, Marin Neto, José Antonio, Silva, João Santana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335880/
https://www.ncbi.nlm.nih.gov/pubmed/22545173
http://dx.doi.org/10.1371/journal.pntd.0001630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335880/
https://www.ncbi.nlm.nih.gov/pubmed/22545173
http://dx.doi.org/10.1371/journal.pntd.0001630

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