Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate

Isoform 4 of the human peptidylarginine deiminase (hPAD4) enzyme may be responsible for the citrullination of antigens in rheumatoid arthritis (RA) and has been shown to be itself the target of disease-specific autoantibodies. Here, we have tested whether the level of serum anti-hPAD4 antibodies in...

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Detalles Bibliográficos
Autores principales: Pollmann, Sylvie, Stensland, Maria, Halvorsen, Eirik Hornes, Sollid, Ludvig M., Kvien, Tore K., Fleckenstein, Burkhard, Molberg, Øyvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336063/
https://www.ncbi.nlm.nih.gov/pubmed/21267570
http://dx.doi.org/10.1007/s00296-010-1765-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336063/
https://www.ncbi.nlm.nih.gov/pubmed/21267570
http://dx.doi.org/10.1007/s00296-010-1765-y

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