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Unfolded protein stress in the endoplasmic reticulum and mitochondria: a role in neurodegeneration
Protein-folding occurs in several intracellular locations including the endoplasmic reticulum and mitochondria. In normal conditions there is a balance between the levels of unfolded proteins and protein folding machinery. Disruption of homeostasis and an accumulation of unfolded proteins trigger st...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336107/ https://www.ncbi.nlm.nih.gov/pubmed/22539924 http://dx.doi.org/10.3389/fnagi.2012.00005 |