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The generation and evaluation of two panels of epitope-matched mouse IgG1, IgG2a, IgG2b and IgG3 antibodies specific for Plasmodium falciparum and Plasmodium yoelii merozoite surface protein 1–19 (MSP1(19))

Murine immunoglobulin G (IgG) plays an important role in mediating protective immune responses to malaria. We still know relatively little about which IgG subclasses protect against this disease in mouse models, although IgG2a and IgG2b are considered to be the most potent and dominate in successful...

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Detalles Bibliográficos
Autores principales: Adame-Gallegos, Jaime R., Shi, Jianguo, McIntosh, Richard S., Pleass, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336205/
https://www.ncbi.nlm.nih.gov/pubmed/22343045
http://dx.doi.org/10.1016/j.exppara.2012.02.003