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Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non-native women at high altitude
Pregnancy at high altitude is associated with a reduction in birth weight of ∼100 g/1000 m of ascent. The underlying mechanisms are unclear but may involve alteration in energy-demanding activities, such as protein synthesis. To test this hypothesis, both in vivo and in vitro approaches were used. P...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336782/ https://www.ncbi.nlm.nih.gov/pubmed/22267338 http://dx.doi.org/10.1096/fj.11-190082 |