Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non-native women at high altitude

Pregnancy at high altitude is associated with a reduction in birth weight of ∼100 g/1000 m of ascent. The underlying mechanisms are unclear but may involve alteration in energy-demanding activities, such as protein synthesis. To test this hypothesis, both in vivo and in vitro approaches were used. P...

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Detalles Bibliográficos
Autores principales: Yung, Hong Wa, Cox, Mathew, Tissot van Patot, Martha, Burton, Graham J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2012
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336782/
https://www.ncbi.nlm.nih.gov/pubmed/22267338
http://dx.doi.org/10.1096/fj.11-190082

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