Haptoglobin-hemoglobin receptor independent killing of African trypanosomes by human serum and trypanosome lytic factors

The haptoglobin-hemoglobin receptor (HpHbR) of African trypanosomes plays a critical role in human innate immunity against these parasites. Localized to the flagellar pocket of the veterinary pathogen Trypanosoma brucei brucei this receptor binds Trypanosome Lytic Factor-1 (TLF-1), a subclass of hum...

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Detalles Bibliográficos
Autores principales: Bullard, Whitney, Kieft, Rudo, Capewell, Paul, Veitch, Nicola J., Macleod, Annette, Hajduk, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Article Addendum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337153/
https://www.ncbi.nlm.nih.gov/pubmed/22286709
http://dx.doi.org/10.4161/viru.3.1.18295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337153/
https://www.ncbi.nlm.nih.gov/pubmed/22286709
http://dx.doi.org/10.4161/viru.3.1.18295

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