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Haptoglobin-hemoglobin receptor independent killing of African trypanosomes by human serum and trypanosome lytic factors

The haptoglobin-hemoglobin receptor (HpHbR) of African trypanosomes plays a critical role in human innate immunity against these parasites. Localized to the flagellar pocket of the veterinary pathogen Trypanosoma brucei brucei this receptor binds Trypanosome Lytic Factor-1 (TLF-1), a subclass of hum...

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Detalles Bibliográficos
Autores principales:	Bullard, Whitney, Kieft, Rudo, Capewell, Paul, Veitch, Nicola J., Macleod, Annette, Hajduk, Stephen L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Article Addendum
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337153/ https://www.ncbi.nlm.nih.gov/pubmed/22286709 http://dx.doi.org/10.4161/viru.3.1.18295

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