Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions

The small GTPase Ras is activated in a high proportion of human cancers. Attempts to clinically block Ras activity through pharmacological means has proven largely ineffective thus far. We employed an inducible mouse model of squamous cell carcinoma (SCC) to study the effect of Ras activation and sh...

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Detalles Bibliográficos
Autores principales: White, Andrew C., Lowry, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2011
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337161/
https://www.ncbi.nlm.nih.gov/pubmed/22545230
http://dx.doi.org/10.4161/sgtp.18088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337161/
https://www.ncbi.nlm.nih.gov/pubmed/22545230
http://dx.doi.org/10.4161/sgtp.18088

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