Cargando…
Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions
The small GTPase Ras is activated in a high proportion of human cancers. Attempts to clinically block Ras activity through pharmacological means has proven largely ineffective thus far. We employed an inducible mouse model of squamous cell carcinoma (SCC) to study the effect of Ras activation and sh...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337161/ https://www.ncbi.nlm.nih.gov/pubmed/22545230 http://dx.doi.org/10.4161/sgtp.18088 |