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Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2

Proteins of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family are activated by various cellular stresses, including DNA damage, premature termination codon and nutritional status, and induce appropriate cellular responses. The importance of PIKK functions in the maintenance of g...

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Detalles Bibliográficos
Autores principales: Izumi, Natsuko, Yamashita, Akio, Ohno, Shigeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337166/
https://www.ncbi.nlm.nih.gov/pubmed/22540023
http://dx.doi.org/10.4161/nucl.18926