Bacterium-like particles as multi-epitope delivery platform for Plasmodium berghei circumsporozoite protein induce complete protection against malaria in mice

BACKGROUND: Virus-like particles have been regularly used as an antigen delivery system for a number of Plasmodium peptides or proteins. The present study reports the immunogenicity and protective efficacy of bacterium-like particles (BLPs) generated from Lactococcus lactis and loaded with Plasmodiu...

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Detalles Bibliográficos
Autores principales: Nganou-Makamdop, Krystelle, van Roosmalen, Maarten L, Audouy, Sandrine AL, van Gemert, Geert-Jan, Leenhouts, Kees, Hermsen, Cornelus C, Sauerwein, Robert W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337279/
https://www.ncbi.nlm.nih.gov/pubmed/22348325
http://dx.doi.org/10.1186/1475-2875-11-50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337279/
https://www.ncbi.nlm.nih.gov/pubmed/22348325
http://dx.doi.org/10.1186/1475-2875-11-50

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