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Loss of HLTF function promotes intestinal carcinogenesis

BACKGROUND: HLTF (Helicase-like Transcription Factor) is a DNA helicase protein homologous to the SWI/SNF family involved in the maintenance of genomic stability and the regulation of gene expression. HLTF has also been found to be frequently inactivated by promoter hypermethylation in human colon c...

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Detalles Bibliográficos
Autores principales: Sandhu, Sumit, Wu, Xiaoli, Nabi, Zinnatun, Rastegar, Mojgan, Kung, Sam, Mai, Sabine, Ding, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337324/
https://www.ncbi.nlm.nih.gov/pubmed/22452792
http://dx.doi.org/10.1186/1476-4598-11-18