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The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in children

BACKGROUND: Patients showed a different response following intravenous midazolam injection. Some children showed irritability or were not sedated by midazolam. We hypothesized that there may be genetic variations of the MDR1 gene, based on the response to midazolam. METHODS: One hundred and ninety-t...

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Detalles Bibliográficos
Autores principales: Byon, Hyo-Jin, Park, Keun-Suk, Park, Yong-Hee, Kim, Jin-Tae, Jung, Chul-Woo, Kim, Hee-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Anesthesiologists 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337379/
https://www.ncbi.nlm.nih.gov/pubmed/22558499
http://dx.doi.org/10.4097/kjae.2012.62.4.332