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Expression of Fraser syndrome genes in normal and polycystic murine kidneys

BACKGROUND: Fraser syndrome (FS) features renal agenesis and cystic kidneys. Mutations of FRAS1 (Fraser syndrome 1) and FREM2 (FRAS1-related extracellular matrix protein 2) cause FS. They code for basement membrane proteins expressed in metanephric epithelia where they mediate epithelial/mesenchymal...

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Detalles Bibliográficos
Autores principales: Kerecuk, Larissa, Long, David A., Ali, Zahabia, Anders, Corina, Kolatsi-Joannou, Maria, Scambler, Peter J., Woolf, Adrian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337421/
https://www.ncbi.nlm.nih.gov/pubmed/21993971
http://dx.doi.org/10.1007/s00467-012-2100-5