Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA

Meiotic DNA double-stranded breaks (DSBs) initiate genetic recombination in discrete areas of the genome called recombination hotspots. DSBs can be directly mapped using chromatin immunoprecipitation followed by sequencing (ChIP-seq). Nevertheless, the genome-wide mapping of recombination hotspots i...

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Detalles Bibliográficos
Autores principales: Khil, Pavel P., Smagulova, Fatima, Brick, Kevin M., Camerini-Otero, R. Daniel, Petukhova, Galina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337440/
https://www.ncbi.nlm.nih.gov/pubmed/22367190
http://dx.doi.org/10.1101/gr.130583.111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337440/
https://www.ncbi.nlm.nih.gov/pubmed/22367190
http://dx.doi.org/10.1101/gr.130583.111

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