Cargando…

Identification of novel causative genes determining the complex trait of high ethanol tolerance in yeast using pooled-segregant whole-genome sequence analysis

High ethanol tolerance is an exquisite characteristic of the yeast Saccharomyces cerevisiae, which enables this microorganism to dominate in natural and industrial fermentations. Up to now, ethanol tolerance has only been analyzed in laboratory yeast strains with moderate ethanol tolerance. The gene...

Descripción completa

Detalles Bibliográficos
Autores principales:	Swinnen, Steve, Schaerlaekens, Kristien, Pais, Thiago, Claesen, Jürgen, Hubmann, Georg, Yang, Yudi, Demeke, Mekonnen, Foulquié-Moreno, María R., Goovaerts, Annelies, Souvereyns, Kris, Clement, Lieven, Dumortier, Françoise, Thevelein, Johan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2012
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337442/ https://www.ncbi.nlm.nih.gov/pubmed/22399573 http://dx.doi.org/10.1101/gr.131698.111

Ejemplares similares

QTL Analysis of High Thermotolerance with Superior and Downgraded Parental Yeast Strains Reveals New Minor QTLs and Converges on Novel Causative Alleles Involved in RNA Processing
por: Yang, Yudi, et al.
Publicado: (2013)

Comparative Polygenic Analysis of Maximal Ethanol Accumulation Capacity and Tolerance to High Ethanol Levels of Cell Proliferation in Yeast
por: Pais, Thiago M., et al.
Publicado: (2013)

Simultaneous Mapping of Multiple Gene Loci with Pooled Segregants
por: Claesen, Jürgen, et al.
Publicado: (2013)

Rapid Evolution of Recombinant Saccharomyces cerevisiae for Xylose Fermentation through Formation of Extra-chromosomal Circular DNA
por: Demeke, Mekonnen M., et al.
Publicado: (2015)

Improved linkage analysis of Quantitative Trait Loci using bulk segregants unveils a novel determinant of high ethanol tolerance in yeast
por: Duitama, Jorge, et al.
Publicado: (2014)

Combining inhibitor tolerance and D-xylose fermentation in industrial Saccharomyces cerevisiae for efficient lignocellulose-based bioethanol production
por: Demeke, Mekonnen M, et al.
Publicado: (2013)

Whole-Genome Transformation of Yeast Promotes Rare Host Mutations with a Single Causative SNP Enhancing Acetic Acid Tolerance
por: Stojiljković, Marija, et al.
Publicado: (2022)

Identification of the major fermentation inhibitors of recombinant 2G yeasts in diverse lignocellulose hydrolysates
por: Vanmarcke, Gert, et al.
Publicado: (2021)

Identification of multiple interacting alleles conferring low glycerol and high ethanol yield in Saccharomyces cerevisiae ethanolic fermentation
por: Hubmann, Georg, et al.
Publicado: (2013)

Polygenic analysis of very high acetic acid tolerance in the yeast Saccharomyces cerevisiae reveals a complex genetic background and several new causative alleles
por: Stojiljkovic, Marija, et al.
Publicado: (2020)

Development of a D-xylose fermenting and inhibitor tolerant industrial Saccharomyces cerevisiae strain with high performance in lignocellulose hydrolysates using metabolic and evolutionary engineering
por: Demeke, Mekonnen M, et al.
Publicado: (2013)

Polygenic Analysis of Tolerance to Carbon Dioxide Inhibition of Isoamyl Acetate “Banana” Flavor Production in Yeast Reveals MDS3 as Major Causative Gene
por: Souffriau, Ben, et al.
Publicado: (2022)

An integrated framework for discovery and genotyping of genomic variants from high-throughput sequencing experiments
por: Duitama, Jorge, et al.
Publicado: (2014)

Cell Immobilization Using Alginate-Based Beads as a Protective Technique against Stressful Conditions of Hydrolysates for 2G Ethanol Production
por: Soares, Raiane C., et al.
Publicado: (2022)

Mechanisms underlying lactic acid tolerance and its influence on lactic acid production in Saccharomyces cerevisiae
por: Peetermans, Arne, et al.
Publicado: (2021)

Development of an industrial yeast strain for efficient production of 2,3-butanediol
por: Huo, Guangxin, et al.
Publicado: (2022)

Engineering tolerance to industrially relevant stress factors in yeast cell factories
por: Deparis, Quinten, et al.
Publicado: (2017)

Whole-Genome Transformation Promotes tRNA Anticodon Suppressor Mutations under Stress
por: Deparis, Quinten, et al.
Publicado: (2021)

In-situ muconic acid extraction reveals sugar consumption bottleneck in a xylose-utilizing Saccharomyces cerevisiae strain
por: Nicolaï, Thomas, et al.
Publicado: (2021)

Polygenic analysis and targeted improvement of the complex trait of high acetic acid tolerance in the yeast Saccharomyces cerevisiae
por: Meijnen, Jean-Paul, et al.
Publicado: (2016)

Exon capture and bulk segregant analysis: rapid discovery of causative mutations using high-throughput sequencing
por: del Viso, Florencia, et al.
Publicado: (2012)

Dissection of genetically complex traits with extremely large pools of yeast segregants
por: Ehrenreich, Ian M., et al.
Publicado: (2010)

Pooled Segregant Sequencing Reveals Genetic Determinants of Yeast Pseudohyphal Growth
por: Song, Qingxuan, et al.
Publicado: (2014)

Polygenic Analysis in Absence of Major Effector ATF1 Unveils Novel Components in Yeast Flavor Ester Biosynthesis
por: Holt, Sylvester, et al.
Publicado: (2018)

Familial segregation of a VSX1 mutation adds a new dimension to its role in the causation of keratoconus
por: Paliwal, Preeti, et al.
Publicado: (2011)

Genomic saturation mutagenesis and polygenic analysis identify novel yeast genes affecting ethyl acetate production, a non-selectable polygenic trait
por: Abt, Tom Den, et al.
Publicado: (2016)

Unique genetic basis of the distinct antibiotic potency of high acetic acid production in the probiotic yeast Saccharomyces cerevisiae var. boulardii
por: Offei, Benjamin, et al.
Publicado: (2019)

A novel AST2 mutation generated upon whole-genome transformation of Saccharomyces cerevisiae confers high tolerance to 5-Hydroxymethylfurfural (HMF) and other inhibitors
por: Vanmarcke, Gert, et al.
Publicado: (2021)

The molecular biology of fruity and floral aromas in beer and other alcoholic beverages
por: Holt, Sylvester, et al.
Publicado: (2018)

Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation
por: Zhang, Gang, et al.
Publicado: (2016)

Causation
Publicado: (1993)

Causation and disease: effect of technology on postulates of causation.
por: Evans, A. S.
Publicado: (1991)

Leech Infestation: The Unusual Cause of Upper Airway Obstruction
por: Mekonnen, Demeke
Publicado: (2013)

Clinically Confirmed Congenital Rubella Syndrome: The Role of Echocardiography
por: Mekonnen, Demeke
Publicado: (2017)

Identification of Novel Alleles Conferring Superior Production of Rose Flavor Phenylethyl Acetate Using Polygenic Analysis in Yeast
por: Trindade de Carvalho, Bruna, et al.
Publicado: (2017)

A Preferentially Segregated Recycling Vesicle Pool of Limited Size Supports Neurotransmission in Native Central Synapses
por: Marra, Vincenzo, et al.
Publicado: (2012)

What’s old is new again: yeast mutant screens in the era of pooled segregant analysis by genome sequencing
por: Curtin, Chris, et al.
Publicado: (2016)

Major sulfonate transporter Soa1 in Saccharomyces cerevisiae and considerable substrate diversity in its fungal family
por: Holt, Sylvester, et al.
Publicado: (2017)

Eumycetoma causative agents are inhibited in vitro by luliconazole, lanoconazole and ravuconazole
por: Nyuykonge, Bertrand, et al.
Publicado: (2022)

Causation and complications
por: Freshwater, M. Felix
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ro9rilis1ak2l8knfihtj3ut9m