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High-Resolution Genomic Profiling of Chromosomal Abnormalities in Human Stem Cells Using the 135 K StemArray

Culturing stem cells for an extended period of time can lead to acquired chromosomal aberrations. Determining the copy number variant (CNV) profile of stem cell lines is critical since CNVs can have dramatic effects on gene expression and tumorigenic potential. Here, we describe an improved version...

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Detalles Bibliográficos
Autores principales: Elliott, Aaron M., Hohenstein Elliott, Kristi A., Kammesheidt, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337514/
https://www.ncbi.nlm.nih.gov/pubmed/22567024
http://dx.doi.org/10.1155/2012/431534