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Glia instruct developmental neuronal remodeling through TGF-βsignaling
Neural circuits are remodeled in response to developmental and environmental cues. Here we show that glia secrets Myoglianin, a TGF-β ligand, to instruct developmental neural remodeling in Drosophila. Glial Myoglianin up-regulates neuronal expression of an ecdysone nuclear receptor that triggers neu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337551/ https://www.ncbi.nlm.nih.gov/pubmed/21685919 http://dx.doi.org/10.1038/nn.2833 |