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Immunogenicity and Protective Efficacy of a Novel Recombinant BCG Strain Overexpressing Antigens Ag85A and Ag85B

Recombinant Bacillus Calmette-Guérin (rBCG) strain is the promising vaccine candidate for tuberculosis (TB) prevention, which aims at providing more enduring and enhanced protection than the parental BCG vaccine. In this study, three rBCG strains overexpressing immunodominant antigens Ag85B (rBCG::8...

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Detalles Bibliográficos
Autores principales: Wang, Chun, Fu, Ruiling, Chen, Zhenhua, Tan, Kun, Chen, Lingxia, Teng, Xindong, Lu, Jia, Shi, Chunwei, Fan, Xionglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337592/
https://www.ncbi.nlm.nih.gov/pubmed/22570667
http://dx.doi.org/10.1155/2012/563838