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Immunogenicity and Protective Efficacy of a Novel Recombinant BCG Strain Overexpressing Antigens Ag85A and Ag85B
Recombinant Bacillus Calmette-Guérin (rBCG) strain is the promising vaccine candidate for tuberculosis (TB) prevention, which aims at providing more enduring and enhanced protection than the parental BCG vaccine. In this study, three rBCG strains overexpressing immunodominant antigens Ag85B (rBCG::8...
Autores principales: | Wang, Chun, Fu, Ruiling, Chen, Zhenhua, Tan, Kun, Chen, Lingxia, Teng, Xindong, Lu, Jia, Shi, Chunwei, Fan, Xionglin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337592/ https://www.ncbi.nlm.nih.gov/pubmed/22570667 http://dx.doi.org/10.1155/2012/563838 |
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