Expression of PAFR as Part of a Prosurvival Response to Chemotherapy: A Novel Target for Combination Therapy in Melanoma

Melanoma cells express the platelet-activating factor receptor (PAFR) and, thus, respond to PAF, a bioactive lipid produced by both tumour cells and those in the tumour microenvironment such as macrophages. Here, we show that treatment of a human melanoma SKmel37 cell line with cisplatin led to incr...

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Detalles Bibliográficos
Autores principales: Onuchic, Ana Claudia, Machado, Camila M. L., Saito, Renata F., Rios, Francisco J., Jancar, Sônia, Chammas, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337612/
https://www.ncbi.nlm.nih.gov/pubmed/22570511
http://dx.doi.org/10.1155/2012/175408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337612/
https://www.ncbi.nlm.nih.gov/pubmed/22570511
http://dx.doi.org/10.1155/2012/175408

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