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Expression of PAFR as Part of a Prosurvival Response to Chemotherapy: A Novel Target for Combination Therapy in Melanoma

Melanoma cells express the platelet-activating factor receptor (PAFR) and, thus, respond to PAF, a bioactive lipid produced by both tumour cells and those in the tumour microenvironment such as macrophages. Here, we show that treatment of a human melanoma SKmel37 cell line with cisplatin led to incr...

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Detalles Bibliográficos
Autores principales:	Onuchic, Ana Claudia, Machado, Camila M. L., Saito, Renata F., Rios, Francisco J., Jancar, Sônia, Chammas, Roger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337612/ https://www.ncbi.nlm.nih.gov/pubmed/22570511 http://dx.doi.org/10.1155/2012/175408

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