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Direct Observation of Cooperative Protein Structural Dynamics of Homodimeric Hemoglobin from 100 ps to 10 ms with Pump–Probe X-ray Solution Scattering

[Image: see text] Proteins serve as molecular machines in performing their biological functions, but the detailed structural transitions are difficult to observe in their native aqueous environments in real time. For example, despite extensive studies, the solution-phase structures of the intermedia...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Hwan, Muniyappan, Srinivasan, Oang, Key Young, Kim, Jong Goo, Nozawa, Shunsuke, Sato, Tokushi, Koshihara, Shin-ya, Henning, Robert, Kosheleva, Irina, Ki, Hosung, Kim, Youngmin, Kim, Tae Wu, Kim, Jeongho, Adachi, Shin-ichi, Ihee, Hyotcherl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337689/
https://www.ncbi.nlm.nih.gov/pubmed/22494177
http://dx.doi.org/10.1021/ja210856v