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Structural and Functional Consequences of Phosphate–Arsenate Substitutions in Selected Nucleotides: DNA, RNA, and ATP

[Image: see text] A recent finding of a bacterial strain (GFAJ-1) that can rely on arsenic instead of phosphorus raised the questions of if and how arsenate can replace phosphate in biomolecules that are essential to sustain cell life. Apart from questions related to chemical stability, there are th...

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Detalles Bibliográficos
Autores principales: Xu, Yu, Ma, Buyong, Nussinov, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337691/
https://www.ncbi.nlm.nih.gov/pubmed/22480264
http://dx.doi.org/10.1021/jp300307u