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Role of Leukotrienes on Protozoan and Helminth Infections

Leukotrienes (LTs), formed by the 5-lipoxygenase-(5-LO-) catalyzed oxidation of arachidonic acid, are lipid mediators that have potent proinflammatory activities. Pharmacologic or genetic inhibition of 5-LO biosynthesis in animals is associated with increased mortality and impaired clearance of bact...

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Detalles Bibliográficos
Autores principales: Rogerio, Alexandre P., Anibal, Fernanda F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337730/
https://www.ncbi.nlm.nih.gov/pubmed/22577251
http://dx.doi.org/10.1155/2012/595694