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Matrix metalloproteinases 2 and 9 increase permeability of sheep pleura in vitro

BACKGROUND: Matrix metalloproteinases (MMPs) 2 and 9 are two gelatinase members which have been found elevated in exudative pleural effusions. In endothelial cells these MMPs increase paracellular permeability via the disruption of tight junction (TJ) proteins occludin and claudin. In the present st...

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Detalles Bibliográficos
Autores principales: Apostolidou, Eleni, Paraskeva, Efrosyni, Gourgoulianis, Konstantinos, Molyvdas, Paschalis-Adam, Hatzoglou, Chrissi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337816/
https://www.ncbi.nlm.nih.gov/pubmed/22424238
http://dx.doi.org/10.1186/1472-6793-12-2