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Angiogenin functionally interacts with p53 and regulates p53 mediated apoptosis and cell survival
Angiogenin, a 14-kDa multi-functional pro-angiogenic growth factor, is up-regulated in several types of cancers. Anti-angiogenin monoclonal antibodies used as antagonists inhibited the establishment, progression, and metastasis of human cancer cells in athymic mice (Olson et al. 1994). Silencing ang...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337890/ https://www.ncbi.nlm.nih.gov/pubmed/22266868 http://dx.doi.org/10.1038/onc.2011.648 |