Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells

Phage display screening allows the study of functional protein–protein interactions at the cell surface, but investigating intracellular organelles remains a challenge. Here we introduce internalizing-phage libraries to identify clones that enter mammalian cells through a receptor-independent mechan...

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Detalles Bibliográficos
Autores principales: Rangel, Roberto, Guzman-Rojas, Liliana, le Roux, Lucia G., Staquicini, Fernanda I., Hosoya, Hitomi, Barbu, E. Magda, Ozawa, Michael G., Nie, Jing, Jr, Kenneth Dunner, Langley, Robert R., Sage, E. Helene, Koivunen, Erkki, Gelovani, Juri G., Lobb, Roy R., Sidman, Richard L., Pasqualini, Renata, Arap, Wadih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337985/
https://www.ncbi.nlm.nih.gov/pubmed/22510693
http://dx.doi.org/10.1038/ncomms1773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337985/
https://www.ncbi.nlm.nih.gov/pubmed/22510693
http://dx.doi.org/10.1038/ncomms1773

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