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The C-terminal helical bundle of the tetrameric prokaryotic sodium channel accelerates the inactivation rate
Most tetrameric channels have cytosolic domains to regulate their functions, including channel inactivation. Here we show that the cytosolic C-terminal region of NavSulP, a prokaryotic voltage-gated sodium channel cloned from Sulfitobacter pontiacus, accelerates channel inactivation. The crystal str...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337986/ https://www.ncbi.nlm.nih.gov/pubmed/22531178 http://dx.doi.org/10.1038/ncomms1797 |