Convergence and coevolution of Hepatitis B virus drug resistance

Treatment with lamivudine of patients infected with hepatitis B virus (HBV) results in a high rate of drug resistance, which is primarily associated with the rtM204I/V substitution in the HBV reverse transcriptase domain. Here we show that the rtM204I/V substitution, although essential, is insuffici...

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Detalles Bibliográficos
Autores principales: Thai, Hong, Campo, David S., Lara, James, Dimitrova, Zoya, Ramachandran, Sumathi, Xia, Guoliang, Ganova-Raeva, Lilia, Teo, Chong-Gee, Lok, Anna, Khudyakov, Yury
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337990/
https://www.ncbi.nlm.nih.gov/pubmed/22510694
http://dx.doi.org/10.1038/ncomms1794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337990/
https://www.ncbi.nlm.nih.gov/pubmed/22510694
http://dx.doi.org/10.1038/ncomms1794

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