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GRiP: a computational tool to simulate transcription factor binding in prokaryotes

Motivation: Transcription factors (TFs) are proteins that regulate gene activity by binding to specific sites on the DNA. Understanding the way these molecules locate their target site is of great importance in understanding gene regulation. We developed a comprehensive computational model of this p...

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Detalles Bibliográficos
Autores principales: Zabet, Nicolae Radu, Adryan, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338021/
https://www.ncbi.nlm.nih.gov/pubmed/22426343
http://dx.doi.org/10.1093/bioinformatics/bts132