A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing

The mechanism of HLA-DM (DM) activity is still unclear. We have shown that DM-mediated peptide release from HLA-DR (DR) is dependent on the presence of exchange peptide. However, DM also promotes a small amount of peptide release in the absence of exchange peptide. Here we show that SDS-PAGE separat...

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Detalles Bibliográficos
Autores principales: Ferrante, Andrea, Gorski, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338121/
https://www.ncbi.nlm.nih.gov/pubmed/22545194
http://dx.doi.org/10.1038/srep00386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338121/
https://www.ncbi.nlm.nih.gov/pubmed/22545194
http://dx.doi.org/10.1038/srep00386

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