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A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing
The mechanism of HLA-DM (DM) activity is still unclear. We have shown that DM-mediated peptide release from HLA-DR (DR) is dependent on the presence of exchange peptide. However, DM also promotes a small amount of peptide release in the absence of exchange peptide. Here we show that SDS-PAGE separat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338121/ https://www.ncbi.nlm.nih.gov/pubmed/22545194 http://dx.doi.org/10.1038/srep00386 |