Cellular Quantitative Structure–Activity Relationship (Cell-QSAR): Conceptual Dissection of Receptor Binding and Intracellular Disposition in Antifilarial Activities of Selwood Antimycins

[Image: see text] We present the cellular quantitative structure–activity relationship (cell-QSAR) concept that adapts ligand-based and receptor-based 3D-QSAR methods for use with cell-level activities. The unknown intracellular drug disposition is accounted for by the disposition function (DF), a m...

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Detalles Bibliográficos
Autores principales: Natesan, Senthil, Wang, Tiansheng, Lukacova, Viera, Bartus, Vladimir, Khandelwal, Akash, Subramaniam, Rajesh, Balaz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338160/
https://www.ncbi.nlm.nih.gov/pubmed/22468611
http://dx.doi.org/10.1021/jm201371y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338160/
https://www.ncbi.nlm.nih.gov/pubmed/22468611
http://dx.doi.org/10.1021/jm201371y

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