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Evaluating the Evidence for Transmission Distortion in Human Pedigrees

Children of a heterozygous parent are expected to carry either allele with equal probability. Exceptions can occur, however, due to meiotic drive, competition among gametes, or viability selection, which we collectively term “transmission distortion” (TD). Although there are several well-characteriz...

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Detalles Bibliográficos
Autores principales: Meyer, Wynn K., Arbeithuber, Barbara, Ober, Carole, Ebner, Thomas, Tiemann-Boege, Irene, Hudson, Richard R., Przeworski, Molly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338262/
https://www.ncbi.nlm.nih.gov/pubmed/22377632
http://dx.doi.org/10.1534/genetics.112.139576