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Haploidization in Saccharomyces cerevisiae Induced by a Deficiency in Homologous Recombination
Diploid Saccharomyes cerevisae strains lacking the RAD52 gene required for homologous recombination have a very high rate of chromosome loss. Two of four isolates subcultured ∼20 times (∼500 cell divisions) became haploid. These strains were capable of mating with wild-type haploids to produce diplo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Genetics Society of America
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338266/ https://www.ncbi.nlm.nih.gov/pubmed/22367034 http://dx.doi.org/10.1534/genetics.111.138180 |