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Loss of Sex and Age Driven Differences in the Gut Microbiome Characterize Arthritis-Susceptible *0401 Mice but Not Arthritis-Resistant *0402 Mice

BACKGROUND: HLA-DRB1*0401 is associated with susceptibility, while HLA-DRB1*0402 is associated with resistance to developing rheumatoid arthritis (RA) and collagen-induced arthritis in humans and transgenic mice respectively. The influence of gut-joint axis has been suggested in RA, though not yet p...

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Detalles Bibliográficos
Autores principales: Gomez, Andres, Luckey, David, Yeoman, Carl J., Marietta, Eric V., Berg Miller, Margret E., Murray, Joseph A., White, Bryan A., Taneja, Veena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338357/
https://www.ncbi.nlm.nih.gov/pubmed/22553482
http://dx.doi.org/10.1371/journal.pone.0036095