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Stress degradation studies and development of stability-indicating TLC-densitometry method for determination of prednisolone acetate and chloramphenicol in their individual and combined pharmaceutical formulations

A rapid and reproducible stability indicating TLC method was developed for the determination of prednisolone acetate and chloramphenicol in presence of their degraded products. Uniform degradation conditions were maintained by refluxing sixteen reaction mixtures for two hours at 80°C using parallel...

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Detalles Bibliográficos
Autores principales: Musharraf, Syed Ghulam, Fatima, Urooj, Sultana, Rahat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338369/
https://www.ncbi.nlm.nih.gov/pubmed/22264235
http://dx.doi.org/10.1186/1752-153X-6-7