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Calpain 3 is important for muscle regeneration: Evidence from patients with limb girdle muscular dystrophies
BACKGROUND: Limb girdle muscular dystrophy (LGMD) type 2A is caused by mutations in the CAPN3 gene and complete lack of functional calpain 3 leads to the most severe muscle wasting. Calpain 3 is suggested to be involved in maturation of contractile elements after muscle degeneration. The aim of this...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338386/ https://www.ncbi.nlm.nih.gov/pubmed/22443334 http://dx.doi.org/10.1186/1471-2474-13-43 |