Calpain 3 is important for muscle regeneration: Evidence from patients with limb girdle muscular dystrophies

BACKGROUND: Limb girdle muscular dystrophy (LGMD) type 2A is caused by mutations in the CAPN3 gene and complete lack of functional calpain 3 leads to the most severe muscle wasting. Calpain 3 is suggested to be involved in maturation of contractile elements after muscle degeneration. The aim of this...

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Detalles Bibliográficos
Autores principales: Hauerslev, Simon, Sveen, Marie-Louise, Duno, Morten, Angelini, Corrado, Vissing, John, Krag, Thomas O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338386/
https://www.ncbi.nlm.nih.gov/pubmed/22443334
http://dx.doi.org/10.1186/1471-2474-13-43

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