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Differences in selective pressure on dhps and dhfr drug resistant mutations in western Kenya

BACKGROUND: Understanding the origin and spread of mutations associated with drug resistance, especially in the context of combination therapy, will help guide strategies to halt and prevent the emergence of resistance. Unfortunately, studies have assessed these complex processes when resistance is...

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Detalles Bibliográficos
Autores principales: McCollum, Andrea M, Schneider, Kristan A, Griffing, Sean M, Zhou, Zhiyong, Kariuki, Simon, Ter-Kuile, Feiko, Shi, Ya Ping, Slutsker, Laurence, Lal, Altaf A, Udhayakumar, Venkatachalam, Escalante, Ananias A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338400/
https://www.ncbi.nlm.nih.gov/pubmed/22439637
http://dx.doi.org/10.1186/1475-2875-11-77