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The RNA-binding protein QKI5 is a direct target of C/EBPα and delays macrophage differentiation
Differentiated macrophages are essential for the innate immune system; however, the molecular mechanisms underlying the generation of macrophages remain largely unknown. Here we show that the RNA-binding protein QKI, mainly QKI-5, is transcriptionally activated in the early differentiated monocytic...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338430/ https://www.ncbi.nlm.nih.gov/pubmed/22398723 http://dx.doi.org/10.1091/mbc.E11-05-0412 |