Cargando…

PDK1 in apical signaling endosomes participates in the rescue of the polarity complex atypical PKC by intermediate filaments in intestinal epithelia

Phosphorylation of the activation domain of protein kinase C (PKC) isoforms is essential to start a conformational change that results in an active catalytic domain. This activation is necessary not only for newly synthesized molecules, but also for kinase molecules that become dephosphorylated and...

Descripción completa

Detalles Bibliográficos
Autores principales: Mashukova, Anastasia, Forteza, Radia, Wald, Flavia A., Salas, Pedro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338434/
https://www.ncbi.nlm.nih.gov/pubmed/22398726
http://dx.doi.org/10.1091/mbc.E11-12-0988

Ejemplares similares