Cargando…

A VE-cadherin–PAR3–α-catenin complex regulates the Golgi localization and activity of cytosolic phospholipase A(2)α in endothelial cells

Phospholipase A(2) enzymes hydrolyze phospholipids to liberate arachidonic acid for the biosynthesis of prostaglandins and leukotrienes. In the vascular endothelium, group IV phospholipase A(2)α (cPLA(2)α) enzyme activity is regulated by reversible association with the Golgi apparatus. Here we provi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Odell, Adam F., Hollstein, Monica, Ponnambalam, Sreenivasan, Walker, John H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338442/ https://www.ncbi.nlm.nih.gov/pubmed/22398721 http://dx.doi.org/10.1091/mbc.E11-08-0694

Ejemplares similares

Differential Localization of VE- and N-Cadherins in Human Endothelial Cells: VE-Cadherin Competes with N-Cadherin for Junctional Localization
por: Navarro, Pilar, et al.
Publicado: (1998)

Regulation of endothelial barrier function by p120-catenin∙VE-cadherin interaction
por: Garrett, Joshua P., et al.
Publicado: (2017)

The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha- catenin with vascular endothelial cadherin (VE-cadherin)
Publicado: (1995)

Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells
por: Ren, Boyang, et al.
Publicado: (2022)

VE-cadherin cleavage by ovarian cancer microparticles induces β-catenin phosphorylation in endothelial cells
por: Thawadi, Hamda Al, et al.
Publicado: (2015)

VE-Cadherin modulates β-catenin/TCF-4 to enhance Vasculogenic Mimicry
por: Delgado-Bellido, Daniel, et al.
Publicado: (2023)

Endothelial permeability and VE-cadherin: A wacky comradeship
por: Gavard, Julie
Publicado: (2014)

VE-Cadherin–Mediated Epigenetic Regulation of Endothelial Gene Expression
por: Morini, Marco F., et al.
Publicado: (2018)

Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α—Ve-Cadherin Pathway
por: Rand, Daniel, et al.
Publicado: (2021)

α-Catenin–mediated cadherin clustering couples cadherin and actin dynamics
por: Chen, Chi-Shuo, et al.
Publicado: (2015)

Endothelial Phosphatase VE-PTP Participates in Vasculogenic Mimicry by Preventing Autophagic Degradation of VE-Cadherin
por: Delgado-Bellido, Daniel, et al.
Publicado: (2020)

Mechanisms Ensuring Endothelial Junction Integrity Beyond VE-Cadherin
por: Duong, Cao Nguyen, et al.
Publicado: (2020)

The Integrin Antagonist Cilengitide Activates αVβ3, Disrupts VE-Cadherin Localization at Cell Junctions and Enhances Permeability in Endothelial Cells
por: Alghisi, Gian Carlo, et al.
Publicado: (2009)

The RNA-binding protein quaking maintains endothelial barrier function and affects VE-cadherin and β-catenin protein expression
por: de Bruin, Ruben G., et al.
Publicado: (2016)

Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function
por: Fearnley, Gareth W., et al.
Publicado: (2019)

αT-Catenin Is a Constitutive Actin-binding α-Catenin That Directly Couples the Cadherin·Catenin Complex to Actin Filaments
por: Wickline, Emily D., et al.
Publicado: (2016)

uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells
por: Biagioni, Alessio, et al.
Publicado: (2020)

Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin
por: Frye, Maike, et al.
Publicado: (2015)

VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism
por: Juettner, Vanessa V., et al.
Publicado: (2019)

Endothelial barrier dysfunction in systemic inflammation is mediated by soluble VE-cadherin interfering VE-PTP signaling
por: Knop, Juna-Lisa, et al.
Publicado: (2023)

The presence of alpha-catenin in the VE-cadherin complex is required for efficient transendothelial migration of leukocytes
por: van Buul, Jaap D., et al.
Publicado: (2009)

Reevaluating αE-catenin monomer and homodimer functions by characterizing E-cadherin/αE-catenin chimeras
por: Bianchini, Julie M., et al.
Publicado: (2015)

Changes in expression of VE-cadherin and MMPs in endothelial cells: Implications for angiogenesis
por: Kiran, Manikantan S, et al.
Publicado: (2011)

VE-cadherin facilitates BMP-induced endothelial cell permeability and signaling
por: Benn, Andreas, et al.
Publicado: (2016)

Cytosolic phospholipase A(2)α–deficient mice are resistant to experimental autoimmune encephalomyelitis
por: Marusic, Suzana, et al.
Publicado: (2005)

Cytosolic Phospholipase A(2)α–deficient Mice Are Resistant to Collagen-induced Arthritis
por: Hegen, Martin, et al.
Publicado: (2003)

Pharmacophore-based discovery of a novel cytosolic phospholipase A(2)α inhibitor
por: Noha, Stefan M., et al.
Publicado: (2012)

Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells
por: Mahammad, Nur, et al.
Publicado: (2021)

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF
por: Nottebaum, Astrid F., et al.
Publicado: (2008)

Discrete Role for Cytosolic Phospholipase A(2)α in Platelets: Studies Using Single and Double Mutant Mice of Cytosolic and Group IIA Secretory Phospholipase A(2)
por: Wong, Dennis A., et al.
Publicado: (2002)

Inhibition of Cytosolic Phospholipase A(2)α (cPLA(2)α) by Medicinal Plants in Relation to Their Phenolic Content
por: Arnold, Eva, et al.
Publicado: (2015)

Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling
por: Huveneers, Stephan, et al.
Publicado: (2012)

Interleukin-2 alters distribution of CD144 (VE-cadherin) in endothelial cells
por: Kim, Dae Won, et al.
Publicado: (2014)

Molecular mechanism of VE-cadherin in regulating endothelial cell behaviour during angiogenesis
por: Nan, Weijin, et al.
Publicado: (2023)

How VE-cadherin goes with the flow
por: Short, Ben
Publicado: (2015)

Predominant Role of Cytosolic Phospholipase A(2)α in Dioxin-induced Neonatal Hydronephrosis in Mice
por: Yoshioka, Wataru, et al.
Publicado: (2014)

Structural basis of phosphatidylcholine recognition by the C2–domain of cytosolic phospholipase A(2)α
por: Hirano, Yoshinori, et al.
Publicado: (2019)

Novel mechanism regulating endothelial permeability via T-cadherin-dependent VE-cadherin phosphorylation and clathrin-mediated endocytosis
por: Semina, Ekaterina V., et al.
Publicado: (2013)

α-Catenin contributes to the strength of E-cadherin–p120 interactions
por: Troyanovsky, Regina B., et al.
Publicado: (2011)

Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin
por: Gong, Haixia, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_k3jurbgda4vmcqirbkj9t3pdg3