CDK2 and PKA Mediated-Sequential Phosphorylation Is Critical for p19INK4d Function in the DNA Damage Response

DNA damage triggers a phosphorylation-based signaling cascade known as the DNA damage response. p19INK4d, a member of the INK4 family of CDK4/6 inhibitors, has been reported to participate in the DNA damage response promoting DNA repair and cell survival. Here, we provide mechanistic insight into th...

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Detalles Bibliográficos
Autores principales: Marazita, Mariela C., Ogara, M. Florencia, Sonzogni, Silvina V., Martí, Marcelo, Dusetti, Nelson J., Pignataro, Omar P., Cánepa, Eduardo T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338453/
https://www.ncbi.nlm.nih.gov/pubmed/22558186
http://dx.doi.org/10.1371/journal.pone.0035638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338453/
https://www.ncbi.nlm.nih.gov/pubmed/22558186
http://dx.doi.org/10.1371/journal.pone.0035638

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