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Hyperlipidemia and Atherosclerotic Lesion Development in Ldlr-Deficient Mice on a Long-Term High-Fat Diet

BACKGROUND: Mice deficient in the LDL receptor (Ldlr (−/−) mice) have been widely used as a model to mimic human atherosclerosis. However, the time-course of atherosclerotic lesion development and distribution of lesions at specific time-points are yet to be established. The current study sought to...

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Detalles Bibliográficos
Autores principales: Ma, Yanling, Wang, Wenyi, Zhang, Jie, Lu, Youli, Wu, Wenyu, Yan, Hong, Wang, Yiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338468/
https://www.ncbi.nlm.nih.gov/pubmed/22558236
http://dx.doi.org/10.1371/journal.pone.0035835