Cargando…

Hyperlipidemia and Atherosclerotic Lesion Development in Ldlr-Deficient Mice on a Long-Term High-Fat Diet

BACKGROUND: Mice deficient in the LDL receptor (Ldlr (−/−) mice) have been widely used as a model to mimic human atherosclerosis. However, the time-course of atherosclerotic lesion development and distribution of lesions at specific time-points are yet to be established. The current study sought to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ma, Yanling, Wang, Wenyi, Zhang, Jie, Lu, Youli, Wu, Wenyu, Yan, Hong, Wang, Yiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338468/ https://www.ncbi.nlm.nih.gov/pubmed/22558236 http://dx.doi.org/10.1371/journal.pone.0035835

Ejemplares similares

Dietary Cholesterol Is Highly Associated with Severity of Hyperlipidemia and Atherosclerotic Lesions in Heterozygous LDLR-Deficient Hamsters
por: Wang, Jinjie, et al.
Publicado: (2019)

Deficiency of CCAAT/Enhancer Binding Protein-Epsilon Reduces Atherosclerotic Lesions in LDLR−/− Mice
por: Okamoto, Ryoko, et al.
Publicado: (2014)

Increased Inflammation in Atherosclerotic Lesions of Diabetic Akita-LDLr (−/−) Mice Compared to Nondiabetic LDLr (−/−) Mice
por: Engelbertsen, Daniel, et al.
Publicado: (2012)

Stimulation of the PD-1 Pathway Decreases Atherosclerotic Lesion Development in Ldlr Deficient Mice
por: Grievink, Hendrika W., et al.
Publicado: (2021)

HVC1 ameliorates hyperlipidemia and inflammation in LDLR(−/−) mice
por: Cheon, Se-Yun, et al.
Publicado: (2017)

Deficiency of Adipocyte IKKβ Affects Atherosclerotic Plaque Vulnerability in Obese LDLR Deficient Mice
por: Lu, Weiwei, et al.
Publicado: (2019)

Agonistic Anti-TIGIT Treatment Inhibits T Cell Responses in LDLr Deficient Mice without Affecting Atherosclerotic Lesion Development
por: Foks, Amanda C., et al.
Publicado: (2013)

Cardiotonic Pills Plus Recombinant Human Prourokinase Ameliorates Atherosclerotic Lesions in LDLR(–/–) Mice
por: Deng, Jing-Na, et al.
Publicado: (2019)

Heterozygous Ldlr-Deficient Hamster as a Model to Evaluate the Efficacy of PCSK9 Antibody in Hyperlipidemia and Atherosclerosis
por: Wu, Yue, et al.
Publicado: (2019)

Surgical fat removal exacerbates metabolic disorders but not atherogenesis in LDLR(−/−) mice fed on high-fat diet
por: Liu, Lin, et al.
Publicado: (2019)

The Cordyceps militaris-Derived Polysaccharide CM1 Alleviates Atherosclerosis in LDLR((-/-)) Mice by Improving Hyperlipidemia
por: Yin, Fan, et al.
Publicado: (2021)

Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR(-/-) Mice on Western Type Diet
por: Kusters, Dennis H. M., et al.
Publicado: (2015)

Vitamin D(3) supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR(−/−) and LDLR(+/+) mice
por: Kheder, Ramiar, et al.
Publicado: (2017)

Worsening of Oxidative Stress, DNA Damage, and Atherosclerotic Lesions in Aged LDLr(−/−) Mice after Consumption of Guarana Soft Drinks
por: Chisté, Layla Aparecida, et al.
Publicado: (2019)

Author Correction: Surgical fat removal exacerbates metabolic disorders but not atherogenesis in LDLR(−/−) mice fed on high-fat diet
por: Liu, Lin, et al.
Publicado: (2020)

Reduced Atherosclerotic Lesion Size in P-Selectin Deficient Apolipoprotein E-Knockout Mice Fed a Chow but Not a Fat Diet
por: Bourdillon, Marie-Claude, et al.
Publicado: (2006)

Loss of GPR40 in LDL receptor-deficient mice exacerbates high-fat diet-induced hyperlipidemia and nonalcoholic steatohepatitis
por: Lu, Zhongyang, et al.
Publicado: (2022)

Uptake of (68)gallium in atherosclerotic plaques in LDLR(-/-)ApoB(100/100 )mice
por: Silvola, Johanna MU, et al.
Publicado: (2011)

Oxidative Stress and Lipid Accumulation Augments Cell Death in LDLR-Deficient RPE Cells and Ldlr (−/−) Mice
por: Sreekumar, Parameswaran Gangadharan, et al.
Publicado: (2022)

Blockade of the BLT1-LTB(4) axis does not affect mast cell migration towards advanced atherosclerotic lesions in LDLr(−/−) mice
por: Depuydt, Marie A. C., et al.
Publicado: (2022)

Polysaccharide CM1 from Cordyceps militaris hinders adipocyte differentiation and alleviates hyperlipidemia in LDLR((+/−)) hamsters
por: Yu, Wen-Qian, et al.
Publicado: (2021)

Antihyperlipidemic potential of diosmin in Swiss Albino mice with high-fat diet induced hyperlipidemia
por: Firdous, Sayeed Mohammed, et al.
Publicado: (2021)

Berberine decreases plasma triglyceride levels and upregulates hepatic TRIB1 in LDLR wild type mice and in LDLR deficient mice
por: Singh, Amar Bahadur, et al.
Publicado: (2019)

Regular Exercise or Changing Diet Does Not Influence Aortic Valve Disease Progression in LDLR Deficient Mice
por: Schlotter, Florian, et al.
Publicado: (2012)

Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr(-/-) Mice Reversible?
por: Lytle, Kelli A., et al.
Publicado: (2016)

High-Fat Diet Enhances Neutrophil Adhesion in LDLR-Null Mice Via Hypercitrullination of Histone H3
por: Osaka, Mizuko, et al.
Publicado: (2021)

Interaction between Sex and LDLR rs688 Polymorphism on Hyperlipidemia among Taiwan Biobank Adult Participants
por: Liu, Yin-Tso, et al.
Publicado: (2020)

Effects of Low Carbohydrate High Protein (LCHP) diet on atherosclerotic plaque phenotype in ApoE/LDLR(−/−) mice: FT-IR and Raman imaging
por: Wrobel, T. P., et al.
Publicado: (2015)

Slowly Digestible Carbohydrate Diet Ameliorates Hyperglycemia and Hyperlipidemia in High-Fat Diet/Streptozocin-Induced Diabetic Mice
por: Chen, Yu-Zhong, et al.
Publicado: (2022)

Metabolomic and Microbial Remodeling by Shanmei Capsule Improves Hyperlipidemia in High Fat Food-Induced Mice
por: Du, Lijing, et al.
Publicado: (2022)

The effects of berberine on hyperhomocysteinemia and hyperlipidemia in rats fed with a long-term high-fat diet
por: Chang, Xin-xia, et al.
Publicado: (2012)

Lipofundin-Induced Hyperlipidemia Promotes Oxidative Stress and Atherosclerotic Lesions in New Zealand White Rabbits
por: Delgado Roche, Livan, et al.
Publicado: (2012)

Data on leukocyte PDZK1 deficiency affecting macrophage apoptosis but not monocyte recruitment, cell proliferation, macrophage abundance or ER stress in atherosclerotic plaques of LDLR deficient mice
por: Yu, Pei, et al.
Publicado: (2018)

RAGE deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in Western type diet-fed Ldlr(−/−) mice
por: Bijnen, Mitchell, et al.
Publicado: (2018)

Serum Amyloid A Facilitates Early Lesion Development in Ldlr(−/−) Mice
por: Krishack, Paulette A, et al.
Publicado: (2015)

Effects of mulberry leaf on experimental hyperlipidemia rats induced by high-fat diet
por: Huang, Jianbo, et al.
Publicado: (2018)

The effect of genistein on lipid levels and LDLR, LXRα and ABCG1 expression in postmenopausal women with hyperlipidemia
por: Zhang, Tao, et al.
Publicado: (2019)

Macrophage deficiency of Akt2 reduces atherosclerosis in Ldlr null mice
por: Babaev, Vladimir R., et al.
Publicado: (2014)

Neutrophil-specific STAT4 deficiency attenuates atherosclerotic burden and improves plaque stability via reduction in neutrophil activation and recruitment into aortas of Ldlr(−/−) mice.
por: Keeter, W. Coles, et al.
Publicado: (2023)

Neutrophil-specific STAT4 deficiency attenuates atherosclerotic burden and improves plaque stability via reduction in neutrophil activation and recruitment into aortas of Ldlr(−/−) mice
por: Keeter, W. Coles, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_gcj1gfgtef0cc2nr2lecq58i1n