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A Novel BAT3 Sequence Generated by Alternative RNA Splicing of Exon 11B Displays Cell Type-Specific Expression and Impacts on Subcellular Localization

BACKGROUND: The human lymphocyte antigen (HLA) encoded BAT3/BAG6 recently attracted interest as a regulator of protein targeting and degradation, a function that could be exerted in the cytosol and in the nucleus. The BAT3 gene was described to consist of 25 exons. Diversity of transcripts can be ge...

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Detalles Bibliográficos
Autores principales: Kämper, Nadine, Kessler, Jörg, Temme, Sebastian, Wegscheid, Claudia, Winkler, Johannes, Koch, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338477/
https://www.ncbi.nlm.nih.gov/pubmed/22558287
http://dx.doi.org/10.1371/journal.pone.0035972