Inherent Interfacial Mechanical Gradients in 3D Hydrogels Influence Tumor Cell Behaviors

Cells sense and respond to the rigidity of their microenvironment by altering their morphology and migration behavior. To examine this response, hydrogels with a range of moduli or mechanical gradients have been developed. Here, we show that edge effects inherent in hydrogels supported on rigid subs...

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Detalles Bibliográficos
Autores principales: Rao, Shreyas S., Bentil, Sarah, DeJesus, Jessica, Larison, John, Hissong, Alex, Dupaix, Rebecca, Sarkar, Atom, Winter, Jessica O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338483/
https://www.ncbi.nlm.nih.gov/pubmed/22558241
http://dx.doi.org/10.1371/journal.pone.0035852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338483/
https://www.ncbi.nlm.nih.gov/pubmed/22558241
http://dx.doi.org/10.1371/journal.pone.0035852

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